- AC Milan vs Atletico Madrid = 29 September 2021 pukul 02:00 WIB
- Porto vs Liverpool = 29 September 2021 pukul 02:00 WIB
- Dortmund vs Sporting = 29 September 2021 pukul 02:00 WIB
Baca Juga: Jadwal Fase Grup Matchday 2 Liga Champion 2021 2022, Ada PSG vs Manchester City
- Real Madrid vs Sheriff = 29 September 2021 pukul 02:00 WIB
- Zenit vs Malmo = 29 September pukul 02:00 WIB
30 September 2021
- Wolfsburg vs Sevilla = 30 September 2021 pukul 23:45 WIB
- Bayern Munchen vs Dynamo Kyiv = 30 September 2021 pukul 02:00 WIB
- Benfica vs Barcelona = 30 September 2021 pukul 02:00 WIB